Fecha/hora: 01/06/2024 16:33:12

Biblioteca(s): | INIA Las Brujas.
Fecha corriente: | 28/11/2018
Fecha de la última actualización: | 28/11/2018
Autoria: | SALINAS, L.M.; BALSEIRO, A.; JIRÓN, W.; PERALTA, A.; MUÑÓZ, D.; FAJARDO, J.; GAYO, E.; MARTÍNEZ, I.Z.; RIET-CORREA, F.; GARDNER, D.R.; GARCÍA MARÍN, J.F.
Afiliación: | LUIS MANUEL SALINAS, Universidad Internacional Antonio de Valdivieso (UNIAV), Rivas, Nicaragua; Facultad de Veterinaria, Universidad de León, Campus de Vegazana, León, Spain.; ANA BALSEIRO, Servicio Regional de Investigación y Desarrollo Agroalimentario (SERIDA), Centro de Biotecnología Animal, Gijón, Asturias, Spain.; WILLIAM JIRÓN, Universidad Nacional Autónoma de Nicaragua (UNAN), León, Nicaragua.; ANA PERALTA, Universidad Nacional Autónoma de Nicaragua (UNAN), León, Nicaragua.; DAVID MUÑÓZ, Universidad Nacional Autónoma de Nicaragua (UNAN), León, Nicaragua.; JORGE FAJARDO, Universidad Nacional Autónoma de Nicaragua (UNAN), León, Nicaragua.; ELENA GAYO, Facultad de Veterinaria, Universidad de León, Campus de Vegazana, León, Spain.; ILEANA ZORHAYA MARTÍNEZ, Facultad de Veterinaria, Universidad de León, Campus de Vegazana, León, Spain; Universidad Popular Autónoma del Estado de Puebla (UPAEP), Mexico.; FRANKLIN RIET-CORREA AMARAL, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; DALE R. GARDNER, Poisonous Plant Research Laboratory, Logan, UT, United States.; JUAN FRANCISCO GARCÍA MARÍN, Facultad de Veterinaria, Universidad de León, Campus de Vegazana, León, Spain.
Título: | Neurological syndrome in goats associated with Ipomoea trifida and Ipomoea carnea containing calystegines.
Año de publicación: | 2018
Fuente/Imprenta: | Toxicon, January 2019, Volume 157, Pages 8-11.
ISSN: | 0041-0101
DOI: | 10.1016/j.toxicon.2018.11.291
Idioma: | Inglés

Notas:

Article history: Received 16 September 2018 // Received in revised form 7 November 2018 // Accepted 9 November 2018 // Available online 14 November 2018.
This work was partially supported by a grant from Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria ( INIA , Spain), reference number E-RTA2013-00013-C04-04 (FEDER co-funded).

Contenido:

ABSTRACT.
A disease characterized by ataxia, tremors and nystagmus had been observed in goats in Nicaragua. The main histologic lesions were loss and neuronal vacuolation of Purkinje cells and Wallerian-like degeneration mainly in the cerebellum, suggesting a glycoprotein storage disease. Ipomoea carnea and Ipomoea trifida found in the paddocks were negative for swainsonine, but contained calystegines at 0.02% and 0.06% suggesting that the disease was caused by these substances, which are competitive inhibitors of &#946;-glucosidase and &#945;-galactosidase activities. 
© 2018 Elsevier Ltd

Palabras-Clave: | CALYSTEGINES; GOAT; IPOMOEA CARNEA; IPOMOEA TRIFIDA; NICARAGUA; POISONING.
Categoría del tema: | --
Registro original: | INIA Las Brujas (LB)
Ejemplares: | LB - (101730-1) - PXI - AP - DD - PP/TOXICON/2019 -  -  - DIS